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Multi-nation Programme on Functional Genomics


Multi-nation Programme on Functional Genomics

The European Science Foundation programme, Integrated Approaches for Functional Genomics, aims to enhance the development and collaboration of functional genomics research in Europe. The programme is designed to bring together a wide range of functional genomics researchers, to help Europe take advantage of new technologies and genomics information by supporting an integrative approach. The unique structure of the programme encourages experts to mix and share their knowledge with others and younger scientists alike. It is designed to facilitate a pan-European approach to research problems and foster collaborations amongst the participating countries.

Set up in 2000, the programme will run for 5 years and is funded by science and research councils in 23 supporting countries. In the UK, the BBSRC, the MRC and NERC all contribute to the funding. It is overseen by a steering committee consisting of a senior scientist representing each country. The chairman is Mike Taussig of the Babraham Institute, Cambridge. The committee meets once a year to evaluate the success of past events and set directions for the upcoming year.

The programme covers all major areas of functional genomicsÖ

● Analysis of phenotypic changes resulting from mutagenesis and gene disruption

● DNA arrays and chips in expression profiling and mutation detection

● Proteomics: protein identification, characterisation, expression and interactions

● Structural genomics: protein structure determination, classification, modelling and docking

● In silico methods for the description of cellular systems by data and literature mining, predictions and simulations

● Standardisation, benchmarking and comparison of different experimental systems

● Data management: databases, interfaces and ontologies

● Combination and integration of functional genomics data to derive new biological knowledge

Programme activities include workshops, training courses, lecture courses and exchange grants for short-term inter-laboratory visits. A web site has been set up specifically to co-ordinate the programme, advertise events and provide the international functional genomics community with valuable resources (see The site contains all relevant information on the events running, including reports from previous meetings. These are circulated to a mailing list. To join the list and receive information on deadlines and meeting updates, please go to the “Join Us” button on the top of each page. This feature also allows scientists to add their details to an open directory where one can search for potential collaborators or experts in certain fields of research. The web site is maintained at the Babraham Institute, Cambridge.

Scientists working in any participating country are eligible to attend events without paying registration fees and the only requirement for exchange grants is that either the host laboratory or the applicant must belong to one of the participating countries. The programme encourages applications from across the continent and funds events in different countries. In 2003 the following workshops and courses have been planned and there is a further call for proposals with a deadline of March 1st 2003.

Functional genomics and disease May 14-17th Prague, Czech Rep
New in vivo imaging modalities for Molecular Biology, Cell Biology and Physiology May 31st – June 4th Roscoff, France
Regulatory and functional RNAs: computational, genomic and structural approaches July 27th – August 8th Benasque, Spain
From gene array to gene-a-row summer
(Date to be finalised)
Leuven, Belgium
Biocrystallography: From gene to drug September 8-11th Trieste, Italy
Data integration in functional genomics and proteomics: application to biological pathways September – mid-October (Date to be finalised ) Geneva, Switzerland

Ample space is always programmed into workshop timetables for discussion time. These small meetings of no more than 60 participants often yield extremely valuable comments and in order to circulate these to …

French Bulldogs in Texas

Caring for French Bulldogs is fairly easy. Frenchies are great house pets and should be kept indoors during hot or cold weather. If the weather is mild, then they can be let outdoors in a fenced area only. Never let a frenchie run free! If you have a pool, fence it off. Most French Bulldogs cannot swim. Buy them a life jacket. Please!!!!!

How to care for your puppy when meal time comes: We feed Grandma Lucy’s dehydrated as it has never been recalled. We also feed Fromm and Merrick small kibble. Please read labels and check this site for recalled food.

Home cooked food is best, but you can find great food with a lot of research. There are a lot of recipes out there…just BING it. (I don’t use Google)

The best toys are very very very hard ones. Moose horns are perfect and they last for years. They will chew up things easily and get stuff lodged in their throat. No rawhide unless they are large items and you are there to supervise to cut off the material when it gets soft. (yuck) Yep, I do it. Anything on the floor is fair game. They will eat anything! I now have a cleaner house do to my dogs. *smile*

Limit the amount of exercise. Because of their pug faces, they can and will overheat. If this happens, use a cold cloth and hold  on their paws one at a time and then their bellies and head. Cool them down slowly. I’ve only had to do this once. Anna loves to chase a dog that we rescued. I now know to limit the time she does this. They are not overly active except in spurts. They spend most of their time loving on you or chewing hard bones. OK…they nap a lot too. These dogs are perfect for apartments or condos.

Grooming is easy also. Do not bathe more than once a week if possible. Less is better. I trim toenails every 2 weeks (can be done weekly to make the quick shorten). I use a battery powered Dremel on the lowest speed. They usually nap while this is being done. I have a mitt that I brush them with almost daily. One side has a special cloth that removes excess hair. Pet stores carry these. I also use an organic shampoo that is very mild or Aveeno baby wash oatmeal fragrance-free (dark blue cap). I never get their heads wet. I clean their heads and face with a wash cloth. Make sure you clean those lovely wrinkles daily if possible. I use a cotton ball with either Witch Hazel or Peroxide. Dry well with a soft cloth when you are done. I clean their ears every 2 weeks also. I use a product that my vet gave me. DO NOT get water in their ears.  Over cleaning will cause problems too. Keep their ears dry by putting cotton balls in them when bathing and you will be fine.

I crate trained mine and I suggest it because it makes house-breaking easier. Also, if there is ever a need for them to be confined, they won’t be upset and stressed over it. I like to be prepared for anything. Life happens! sigh… We let 3 dogs at a time sleep with us. Crates serve a purpose though, so I suggest people training pups to be comfy with them.

When house training, I use Wee Wee pads from Tractor Supply Co. I make a large square with them and then I start making the square smaller and smaller. Puppies

French bulldog puppy progression

Week 1:        I am sleeping, eating and snuggling with Mom.
What more could a newborn ask for? I’m full, warm, clean and loved by all!

Week 2:        I’m so fat! All I can do is move like a baby seal…and I look like one too. My 1st photo shoot happens  this week …sigh. Also, my eyes are opening and what a world. At least I can see where I’m going…sort of.  My mom is really keeping me all clean and oh so cute.

Week 3:  My human mom Nancy is having to help with keeping me and my bed clean. My siblings are sooooo messy!  Mom Nancy is washing 3 loads a day so we can have a clean bed. whew…

Week 4:        Now is the time to let Mom Nancy know if you want to adopt me. Please make sure your application has been emailed or faxed to her. I’m now on the move a bit more. You can see me getting up on my legs more now. I’m learning social skills now. Playtime is so fun…but I get tired easy and just fall asleep where I’m at. I am getting my baby teeth in and Mom will begin weaning me soon. Mom Nancy gives me extra nurishment too as Mom doesn’t like my new teeth very much. sigh…

This is optional but you can send me a puppy blanket and a pillow case or t-shirt with your scent on it. This will help me get use to you before we meet. Something you have slept with or a t-shirt you have worked out in works well too. Be sure to send the item  in a zip-lock bag. Having your scent with me will help me to know you before we meet…and I will bond with you even quicker!

Week 5:  I’m doing lots of playing and socializing right now. I get to go outside if it is nice and play in my playpen. Outside is so interesting and fun! I’m learning to use wee wee pads too. You are welcome to come meet me anytime you want. I’d love to show you my room and my toys. You can meet my Mommy, Daddy and mom Nancy too!

Week 6:           I get my 1st real BATH this week. My potty training is coming along. I’m doing my best but sometimes I make a mistake. I’m eating softened kibble too. Mom Nancy feeds me Fromm Gold Puppy kibble. I love it!  She order’s it from Chewy’

Week 7:         I’m learning to walk in a harness with a leash. Mom Nancy says I’m such a smart puppy. I think so too.

Week 8:         I might be ready to come home now. Have you read all of the “Caring for Frenchies” page? Are you ready for me? Have you PUPPY PROOFED the house? Is my bed and play area all ready? Do you have Nylabone and or Donkey Kong toys for me??? I can’t have rawhide. I might choke on it. MOST important…do you have my food? Mom Nancy gives you some when you come to get me. She  knows how I love to eat.

My Mom Nancy may decide  that I need to stay with my Mom a little longer. I might not weigh enough or might need a little more time perfecting my eating habits. Personally, I think Mom Nancy just doesn’t want to see me leave. She loves me sooooo much. I am looking forward to coming home with you tho!

Let Mom Nancy know if you need anything else before I get there. You will get a copy …

Frenchies are expensive to breed and raise period!

People who raise French Bulldogs do so for either the love of the breed or for money. Those who do so for love spend what they feel is needed in order to have healthy pups. Those who do it for the money spend as little as possible. They just want what appears to be a healthy puppy to sell for as much money as possible, even though they usually sell them cheaper than a lot of other breeders. This is my opinion. The prices on my pups fall in between the high dollar show prices and the low ball money grubbers. Why? Because I just wanted to sell good quality French Bulldog puppies at  prices that I might be able to make a small profit on and yet help those wanting such dogs to boot. I think you ought to be able to get a really good Frenchie pup at less than $4,000.00 for goodness sakes.  I’m an honest person, and I’d say anyone that puts as much work into my litters as I do, hopes to make a profit at some point.   Below are the so called clinical reasons for the high prices of French Bulldog puppies:

1.) The vast majority cannot breed on their own. Stud fees run from $500 to $2500 and they have to be artificially inseminated ($150 per at 4 to 5 times). This brings on more expense as the female will under go tests to find out when she is ovulating. This can cost up to $750.00 depending on how many blood tests are taken. IF she takes and carries the pups to full term, then a c-section ($800.00) is scheduled. She cannot deliver naturally. If the pups are taken too soon, they will not be fully developed and will die. The mother will also not  come in with milk which is vital to their health. If taken too late, they will detach from the placenta and suffocate or get stuck in the birth canal…leading to their death and sometimes the death of their mother. If everything, goes as planned, you still can end up with complications leading to bottle feeding and cleaning their private parts in order for them to urinate and pass stools. The average litter size is 3 puppies.

2.) I’m tired, so I’ll post more later.…

Pro-Bio Faraday Partnership

Pro-Bio Faraday Partnership

A Faraday Partnership helps in promotion of improved interactive sessions between the UK Science, engineering and technology based program with the aim of process innovation. It brings all the researchers and scientists together for involvement of organizations, societies and government agencies.

Faraday Partnerships give strength to the technological derivations and new product developments. The active players progress under the common sector theme and technology with some pre-defined common targets and working methods. It makes the innovation for effective use of resources with sectional and self-interested group. Faraday partnerships have key importance to the industrial progress of the UK.

Pro-Bio Faraday Partnership


The main aim behind the Pro-Bio Faraday Partnership is to undertake safety improvements, environmental and economic industry. It also focuses on the development of new technology and implementing it within different industries. Pro-Bio makes target on the companies using bio-catalysis and the ones not having expertise for realizing the whole potential of the faster developing field. Pro-Bio activities are split into two sections: aiming at generic activities and helping the individual members. for related information, visit :

Generic activities: Research programs are conducted on regular basis to administer the results. There are many submissions done for producing technology based reports each year. Workshops are held every year for providing a common platform to the experts for presenting information to the community. Pro-bio also interacts with the external organizations and hold joint events for getting assistance on the joint programs. There are technology roadmaps made for the strategic advancements.

Company specific/Individual Activities: All companies are visited by the technology translator. There are potential solutions meant for assisting the companies to gauge best benefits out of bio-catalysis. There is assistance for identification of potential grants and funds for demonstration projects, financial assistance and training opportunities. The experts perform the translations on behalf of Pro-Bio to begin the new initiatives.…